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| 1488 |
| | | Bartolomeu Dias, sailing for the king of Portugal, becomes the first European navigator to round the Cape of Good Hope | |
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| c. 1500 |
| | | The Portuguese establish trading posts in east Africa, on the coast of Mozambique | |
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| 1503 |
| | | The Portuguese set up a trading post on the east African island of Zanzibar | |
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| from 1517 |
| | | From Bosnia to Egypt and Arabia, the Ottoman Turks now rule the largest Muslim empire since the early caliphate - and will frequently use the title of caliph to assert their authority within Sunni Islam | |
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| c. 1550 |
| | | Africans, bought in the Portuguese trading posts of west Africa, are shipped across the Atlantic as slaves | |
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| 1638 |
| | | The French build a trading station on the estuary of the Senegal river in west Africa | |
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| 1652 |
| | | Jan van Riebeeck establishes a Dutch settlement at the Cape of Good Hope | |
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| 1657 |
| | | The Dutch in South Africa purchase slaves to do domestic and agricultural work | |
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| 1661 |
| | | The British establish Fort James on an island in the Gambia river | |
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| 1698 |
| | | A fleet from Oman evicts the Portuguese from Mombasa and Zanzibar | |
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